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The project is developed and maintained by the Graphics and Vision Research group, University of Basel in collaboration with Shapemeans GmbH. The current maintainers of the project (people who can merge pull requests) are:

Scalismo is closely related to the statismo project, and some of the scalismo developers are also actively working on statismo. In fact, scalismo had been started as an attempt to provide the core functionality of Statismo and the ITK registration toolkit, but without the complexity that is induced by these toolkits.

The design of the registration approach used in scalismo is strongly influenced by ITK and Elastix.